Peptide Database

Peptide NameDermadistinctin-L

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC130H221N37O37S

DescriptionStandard

        ALWKTLLKNVGKAAGKAALNAVTDMVNQ
    

Molecular Weight2926.44 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.60

Charge Density (pH 7.0) 0.0998

GRAVY Index0.15

Hydrophobic Moment 0.65

Boman Index0.12

Instability Index0.25

Aliphatic Index 108.21

Aromaticity 0.0357

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1219.01

LogP -11.86

H-bond Donors 41.0

H-bond Acceptors 41.0

Rotatable Bonds 100.0

Heavy Atoms 205.0

Ring Count 2.0

Amide Bonds 31.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0348574 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa distincta [Animal]

FamilyDermaseptin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative

TargetT.cruzi

RECORD: Rec_0377426 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa distincta [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic

TargetStaphylococcus aureus

Activity1.3 μM

MethodMIC

RECORD: Rec_0377562 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa distincta [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic

TargetEscherichia coli

Activity2.5 μM

MethodMIC

RECORD: Rec_0378468 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa distincta [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiprotozoal

TargetCandida guilliermondii

Activity21.8 μM

MethodMIC

RECORD: Rec_0384995 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa distincta [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic

TargetPseudomonas aeruginosa

Activity40 μM

MethodMIC

FIRST PREV 1 ... 5 6 7 8 NEXT LAST

Showing 5 records on this page Ã‚Â· Page 7 of 8