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MYP_093386
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Basic Information
Dermadistinctin-L
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C130H221N37O37S
Standard
Sequence
ALWKTLLKNVGKAAGKAALNAVTDMVNQ
Physicochemical Analysis
2926.44 Da
10.00
2.79
2.60
0.0998
0.15
0.65
0.12
0.25
108.21
0.0357
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1219.01
-11.86
41.0
41.0
100.0
205.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0292250 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiprotozoal
Pseudomonas aeruginosa
40 μM
MIC
PMID10477123;12379643;17409003;17442605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10477123/
RECORD: Rec_0294799 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0309346 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
PMID10477123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10477123/
RECORD: Rec_0331648 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiprotozoal
Staphylococcus aureus
1.3 μM
MIC
PMID10477123;12379643;17409003;17442605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10477123/
RECORD: Rec_0334461 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa distincta [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis
PMID10477123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10477123/
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