Peptide Database

Peptide NameCcl (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length136 amino acids

Chemical FormulaC517H807N173O186S2

DescriptionStandard

        MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSGPGWGTTHTPNGDIHNYNPGEFGHGGNKPGGNGGNSGNHRGSSGGRQSSATAMAFGLPALATPGSGGLALAVSGDALSAAVADVLAALKGAV
    

Molecular Weight12486.12 Da

Isoelectric Point (pI)6.96

Net Charge (pH 7.0)-0.06

Net Charge (pH 7.4) -0.54

Charge Density (pH 7.0) -0.0004

GRAVY Index-0.50

Hydrophobic Moment 0.40

Boman Index0.12

Instability Index24.89

Aliphatic Index 47.50

Aromaticity 0.0294

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5628.01

LogP -99.49

H-bond Donors 189.0

H-bond Acceptors 193.0

Rotatable Bonds 398.0

Heavy Atoms 878.0

Ring Count 19.0

Amide Bonds 149.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0220037 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyColicin/Bacteriocin

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence