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MYP_093320
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Basic Information
Scolopendin 2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C81H141N27O18
Standard
Sequence
AGLQFPVGRIGRLLRK
Physicochemical Analysis
1781.16 Da
12.00
3.79
3.61
0.2372
0.06
0.85
-0.06
55.84
121.88
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
745.84
-5.64
27.0
22.0
60.0
126.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020546 VERIFIED: YES
Provenance & Taxonomy
Chinese red-headed centipede [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 25923
25 μM
MIC
PaperScolopendin 2, a cationic antimicrobial peptide from centipede, and its membrane-active mechanism.
RECORD: Rec_0040156 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
0 % hemolysis at 100 μM
Hemolysis
PMID25462167 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25462167/
RECORD: Rec_0045270 VERIFIED: YES
Provenance & Taxonomy
Chinese red-headed centipede [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
fungi Candida albicans ATCC 90028
6.3 μM
MIC
PaperScolopendin 2, a cationic antimicrobial peptide from centipede, and its membrane-active mechanism.
RECORD: Rec_0064567 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Scolopendin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperBiochim Biophys Acta. 2015;1848(2):634-642 | http://europepmc.org/abstract/med/25462167 PMID25462167 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25462167/
RECORD: Rec_0095142 VERIFIED: NO
Provenance & Taxonomy
Scolopendra subspinipes [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Penicillamine
Bio-Activity Profile
Antimicrobial
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