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MYP_093289
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Basic Information
YIK(625-656)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
32 amino acids
C184H292N44O58S
Standard
Sequence
EMTWEEWEKKIEEYIKKIEEILKKSQNQQIDL
Physicochemical Analysis
4080.61 Da
4.73
-3.15
-3.34
-0.0984
-1.30
0.75
-0.24
68.53
85.31
0.0938
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1721.87
-9.89
57.0
56.0
149.0
287.0
5.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0173026 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Acute myeloid leukemia AML-M7
PMID30901967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30901967/
RECORD: Rec_0184605 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 30901967 PMID30901967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30901967/
RECORD: Rec_0192690 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1 NL4-3 D36G
PMID30901967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30901967/
RECORD: Rec_0208349 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1 NL4-3 (5 HP23-Resistant Strains,WT,E49K,E49K/N126K,D36G/E49K/N126K,L34S/D36G/E49K/E136G):inhibition of virus infection in MT-2 cells
0.000856-0.005286 μM
IC50
PaperPubMed PMID: 30901967 PMID30901967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30901967/
RECORD: Rec_0238328 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1 BaL
PMID30901967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30901967/
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