Peptide Database

Peptide Namekappa-Theraphotoxin-Pg1a

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Venom / Toxin ▸ General toxin ▸ huwentoxin-1 family

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC178H254N44O45S7

DescriptionStandard

        EGECGGFWWKCGSGKPACCPKYVCSPKWGLCNFPMP
    

Molecular Weight3954.64 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)1.78

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0493

GRAVY Index-0.27

Hydrophobic Moment 0.29

Boman Index0.14

Instability Index62.33

Aliphatic Index 21.67

Aromaticity 0.1667

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1367.70

LogP -10.55

H-bond Donors 51.0

H-bond Acceptors 54.0

Rotatable Bonds 116.0

Heavy Atoms 274.0

Ring Count 14.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420104 VERIFIED: YES

Provenance & Taxonomy

OrganismChilobrachys guangxiensis [Animal]

Familyhuwentoxin-1 family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-19; 11-24; 18-31

Bio-Activity Profile

Function

Toxin Venom huwentoxin-1 family Ion channel inhibitor Pathogenesis-associated

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