Peptide Database

Peptide NameBrevicidine

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC70H102N18O17

DescriptionStandard

        NYWKKGKWTIGS
    

Molecular Weight1467.67 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.2297

GRAVY Index-1.34

Hydrophobic Moment 0.35

Boman Index-0.11

Instability Index-26.15

Aliphatic Index 32.50

Aromaticity 0.2500

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 596.84

LogP -3.93

H-bond Donors 22.0

H-bond Acceptors 20.0

Rotatable Bonds 47.0

Heavy Atoms 105.0

Ring Count 5.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0362476 VERIFIED: YES

Provenance & Taxonomy

OrganismBrevibacillus laterosporus [Bacterium]

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermLipidation

C-TermEsterification

Other ModsWarning: three ornithines at positions 4,5, and 7 are represented with K in the sequence

Bio-Activity Profile

Function

Antimicrobial

TargetKlebsiella pneumoniae LMG20218

Activity2 μg/mL

MethodMIC

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