Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length297 amino acids

Chemical FormulaC1487H2334N400O421S7

DescriptionStandard

        TNPGFMVRITQAGLDYAHQQGMAILEKELAQLKLPDISGDSRILRVGKVRYEVSRLRLPNFRLPHSRITPISNVGLQVSISNAFAELDGDWRVKFAFIRDHGSFNLKVENVYIKINLKLGSDTTGKPTISTSACSASISKVRVLFSGKLGWLYNLFHSVIESRLRKILEDKVCDNVAKSVHNELQTYIQTLPGTGGLQVGLGAALASFSQPLSNVLICGEFYSLAHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTAGIAYHKAGALVFEITDAMIPKETGFRLETSVFSAFIPQ
    

Molecular Weight32775.32 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)7.09

Net Charge (pH 7.4) 6.39

Charge Density (pH 7.0) 0.0239

GRAVY Index0.04

Hydrophobic Moment 0.64

Boman Index0.10

Instability Index29.64

Aliphatic Index 96.20

Aromaticity 0.1010

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 24535.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0410522 VERIFIED: NO

Provenance & Taxonomy

OrganismCinclus mexicanus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria