Peptide Database

Peptide Namechassatide C9

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC133H214N34O42S6

DescriptionStandard

        GIPCGESCVFIPCVTTVIGCSCKDKVCYNN
    

Molecular Weight3153.71 Da

Isoelectric Point (pI)6.03

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0099

GRAVY Index0.59

Hydrophobic Moment 0.33

Boman Index0.22

Instability Index12.01

Aliphatic Index 77.67

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1203.61

LogP -14.01

H-bond Donors 46.0

H-bond Acceptors 48.0

Rotatable Bonds 98.0

Heavy Atoms 215.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041853 VERIFIED: YES

Provenance & Taxonomy

OrganismChassalia chartacea [Plant]

FamilyCyclotide

Tax ID137261

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Antibacterial Cytotoxic Hemolytic Anti-Gram-positive

TargetStaphylococcus aureus

RECORD: Rec_0260927 VERIFIED: YES

Provenance & Taxonomy

OrganismChassalia chartacea [Plant]

FamilyCyclotide

Tax ID137261

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Antibacterial Cytotoxic Hemolytic Anti-Gram-positive

TargetStaphylococcus epidermidis

RECORD: Rec_0275047 VERIFIED: NO

Provenance & Taxonomy

OrganismChassalia chartacea [Plant]

FamilyCyclotide

Structure & Mods

Configbackbone-cyclized cyclotide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0278911 VERIFIED: YES

Provenance & Taxonomy

OrganismChassalia chartacea [Plant]

FamilyCyclotide

Tax ID137261

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Cytotoxic Hemolytic

Targetand ?Escherichia coli