Peptide Database

Peptide NameDihydroorotate dehydrogenase (quinone); mitochondrial (EC 1.3.5.2) (Haptoglobin)

Function Ontology

Antimicrobial

Enzyme / Catalytic activity ▸ Oxidoreductase

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length740 amino acids

Chemical FormulaC3607H5743N997O1068S22

DescriptionStandard

        MAWRQLKKRVQDAVVILGGGGLLFTSYLTAMGDEHFYAEHLMPAMQRLLDPESAHRLAVRVTSLGLLPRATFQESDMLEVRVLGHRFRNPIGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLLARQEKQARLTEEGLPLGINLGKNKTSVDAAADYTEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRHLLAKVLQERDALQGAHKPAVLVKIAPDLTAQDKEDIASVVKELGIDGLIITNTTVSRPASLQGALRSEIGGLSGKPLRDLSTQTIREMYALTQGGVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTYRGPPVVGMIKRELEALLKEQGFTRITDAIGADHRRALGAVIALLLWGQLFAEDTGSEATNNTEVSLPKPPVIENGYVEHMIRYQCKPFYKLHTEGDGVYTLNSEKHWTNKAVGEKLPECEAVCGKPKNPVDQVQRIMGGSVDAKGSFPWQAKMVSHHNLTSGATLINEQWLLTTAKNLFLGHKDDAKANDIAPTLKLYVGKNQLVEVEKVVLHPDYSKVDIGLIKLKQKVPIDERVMPICLPSKDYAEVGRIGYVSGWGRNSNFNFTELLKYVMLPVADQDKCVQHYEGSTVPEKKSPKSPVGVQPILNEHTFCAGMSKFQEDTCYGDAGSAFAVHDQDEDTWYAAGILSFDKSCTVAEYGVYVKVPSVLAWVQETIAGN
    

Molecular Weight80868.65 Da

Isoelectric Point (pI)6.72

Net Charge (pH 7.0)-1.73

Net Charge (pH 7.4) -3.29

Charge Density (pH 7.0) -0.0023

GRAVY Index-0.20

Hydrophobic Moment 0.71

Boman Index0.04

Instability Index34.71

Aliphatic Index 92.74

Aromaticity 0.0689

Extinction Coeff. Reduced 78270.00

Extinction Coeff. Oxidized 78770.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247302 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDihydroorotate dehydrogenase; Type 2 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antioxidant Oxidoreductase Non-hemolytic