Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC360H581N101O94S9

DescriptionStandard

        MRIAVLLFAILFFMSQVLPVRGNFKEICERPNGSCRKYCIEKEVYVGTCLDGHPCCLPMGNQPRIKGTRPGL
    

Molecular Weight8116.67 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.16

Charge Density (pH 7.0) 0.0630

GRAVY Index0.09

Hydrophobic Moment 0.50

Boman Index0.06

Instability Index32.59

Aliphatic Index 87.92

Aromaticity 0.0833

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3104.17

LogP -25.25

H-bond Donors 112.0

H-bond Acceptors 109.0

Rotatable Bonds 265.0

Heavy Atoms 564.0

Ring Count 13.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078186 VERIFIED: NO

Provenance & Taxonomy

OrganismSciurus vulgaris [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence