Peptide Database

Peptide Nameomega-Conotoxin PnVIA

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC141H209N35O43S6

DescriptionStandard

        GCLEVDYFCGIPFANNGLCCSGNCVFVCTPQ
    

Molecular Weight3274.77 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.30

Net Charge (pH 7.4) -2.59

Charge Density (pH 7.0) -0.0741

GRAVY Index0.69

Hydrophobic Moment 0.30

Boman Index0.32

Instability Index19.37

Aliphatic Index 69.03

Aromaticity 0.1290

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1226.39

LogP -13.53

H-bond Donors 45.0

H-bond Acceptors 47.0

Rotatable Bonds 98.0

Heavy Atoms 225.0

Ring Count 6.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320145 VERIFIED: NO

Provenance & Taxonomy

OrganismConus pennaceus [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-20; 9-24; 19-28

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0420580 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic