Peptide Database

Peptide NameHBD3 [C11,18,23,33,40,41F]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC252H401N75O59

DescriptionStandard

        GIINTLQKYYFRVRGGRFAVLSFLPKEEQIGKFSTRGRKFFRRKK
    

Molecular Weight5425.35 Da

Isoelectric Point (pI)11.65

Net Charge (pH 7.0)10.76

Net Charge (pH 7.4) 10.54

Charge Density (pH 7.0) 0.2391

GRAVY Index-0.66

Hydrophobic Moment 0.76

Boman Index-0.24

Instability Index41.61

Aliphatic Index 67.11

Aromaticity 0.1778

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2249.60

LogP -18.15

H-bond Donors 83.0

H-bond Acceptors 70.0

Rotatable Bonds 188.0

Heavy Atoms 386.0

Ring Count 9.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383304 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922

Activity9.4 μg/mL

MethodLC50

RECORD: Rec_0424299 VERIFIED: YES