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MYP_093079
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Basic Information
HBD3 [C11,18,23,33,40,41F]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
45 amino acids
C252H401N75O59
Standard
Sequence
GIINTLQKYYFRVRGGRFAVLSFLPKEEQIGKFSTRGRKFFRRKK
Physicochemical Analysis
5425.35 Da
11.65
10.76
10.54
0.2391
-0.66
0.76
-0.24
41.61
67.11
0.1778
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2249.60
-18.15
83.0
70.0
188.0
386.0
9.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0209365 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Rabbit erythrocytes
3-100 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/18350527/ PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
RECORD: Rec_0302628 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
10.1 μg/mL
LC50
PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
RECORD: Rec_0323051 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923[LC = 24.4 microg/ml
PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
RECORD: Rec_0362827 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2010/0048469 A1 Evidence URLhttps://patents.google.com/patent/US20100048469A1/en PatentUS 2010/0048469 A1
RECORD: Rec_0373625 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus cereus NCTC 2599
9.4 μg/mL
LC50
PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
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