Peptide Database

Peptide NameSLAY-screened peptide P63

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC113H162N28O34S

DescriptionStandard

        YDLDRGCAYNLLVYAERYYQ
    

Molecular Weight2488.73 Da

Isoelectric Point (pI)4.56

Net Charge (pH 7.0)-1.25

Net Charge (pH 7.4) -1.48

Charge Density (pH 7.0) -0.0625

GRAVY Index-0.58

Hydrophobic Moment 0.45

Boman Index-0.08

Instability Index23.80

Aliphatic Index 83.00

Aromaticity 0.2500

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1039.25

LogP -6.77

H-bond Donors 38.0

H-bond Acceptors 34.0

Rotatable Bonds 77.0

Heavy Atoms 176.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407990 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/