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MYP_093045
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HPV
Antiviral ▸ Antiviral mechanism ▸ Pseudovirus inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
49 amino acids
C244H403N85O66S5
Standard
Sequence
GRRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDSPIQCIQA
Physicochemical Analysis
5743.67 Da
11.24
8.72
8.45
0.1780
-0.85
0.60
-0.34
93.55
53.67
0.0612
11000.00
11250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2507.18
-29.41
93.0
80.0
190.0
400.0
9.0
55.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0323581 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 34.7%, E 0.0%, T 34.7%, C 30.6% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0338530 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Transferrin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID11254635 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11254635/
RECORD: Rec_0356348 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
10-46, 20-37
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 17481742 PMID17481742 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17481742/
RECORD: Rec_0365921 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0384396 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Lactoferricin
9606
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
allo-residue reported
Bio-Activity Profile
Antimicrobial Anticancer
S. mutants, Bacillus subtilis, Pseudomonas aeruginosa, and Escherichia coli
32 μg/mL
MIC
PaperLactoferricin of bovine origin is more active than lactoferricins of human, murine and caprine origin.
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