Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 18

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC523H853N167O158S7

DescriptionStandard

        MRTLALLAALLLLVLQAQTQKSEKAADQVPAQDQPEAEFQEVIISFGGNERSAQNETALQEASTCRCRVFCHFRERRSGTCAGRGIQNRLCCPRRPPNRFRPTVAQDFI
    

Molecular Weight12232.85 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)3.55

Net Charge (pH 7.4) 3.18

Charge Density (pH 7.0) 0.0326

GRAVY Index-0.42

Hydrophobic Moment 0.70

Boman Index-0.15

Instability Index53.08

Aliphatic Index 75.32

Aromaticity 0.0550

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5317.98

LogP -62.42

H-bond Donors 189.0

H-bond Acceptors 170.0

Rotatable Bonds 409.0

Heavy Atoms 855.0

Ring Count 13.0

Amide Bonds 123.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0263363 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal