Peptide Database

Peptide NameDermatoxin-B1 (DRT-B1) (Dermatoxin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC370H600N96O120S2

DescriptionStandard

        MAFLKKSLFLVLFLGLVPLSLCESEKREGENEEEQEDDQSEEKRSLGSFLKGVGTTLASVGKVVSDQFGKLLQAGQG
    

Molecular Weight8377.42 Da

Isoelectric Point (pI)4.73

Net Charge (pH 7.0)-4.49

Net Charge (pH 7.4) -4.74

Charge Density (pH 7.0) -0.0582

GRAVY Index-0.23

Hydrophobic Moment 0.65

Boman Index0.02

Instability Index52.81

Aliphatic Index 92.34

Aromaticity 0.0649

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3517.81

LogP -35.67

H-bond Donors 120.0

H-bond Acceptors 118.0

Rotatable Bonds 297.0

Heavy Atoms 588.0

Ring Count 6.0

Amide Bonds 82.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0246321 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa bicolor [Animal]

FamilyDermatoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Mollicute Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetSalmonella Typhimurium

RECORD: Rec_0251688 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa bicolor [Animal]

FamilyDermatoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Mollicute Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetA. laidlawii

RECORD: Rec_0413256 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa bicolor [Animal]

FamilyDermatoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Mollicute Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. melliferum

FIRST PREV 1 2

Showing 3 records on this page Ã‚Â· Page 2 of 2