Peptide Database

Peptide NameBasiliximab

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Immunomodulation ▸ Immunosuppressive

Standard StatusStandard

Sequence Length242 amino acids

Chemical FormulaC1160H1769N301O356S10

DescriptionStandard

        QLQQSGTVLARPGASVKMSCKASGYSFTRYWMHWIKQRPGQGLEWIGAIYPGNSDTSYNQKFEGKAKLTAVTSASTAYMELSSLTHEDSAVYYCSRDYGYYFDFWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPPKSCDKTHTCPPCPAPELLGGPSVFLF
    

Molecular Weight25947.91 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)5.13

Net Charge (pH 7.4) 4.51

Charge Density (pH 7.0) 0.0212

GRAVY Index-0.24

Hydrophobic Moment 0.68

Boman Index0.09

Instability Index50.38

Aliphatic Index 63.64

Aromaticity 0.1116

Extinction Coeff. Reduced 46870.00

Extinction Coeff. Oxidized 47245.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350356 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Mus musculus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10090

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Immunosuppressive IL-2 receptor antagonist

Half-Life7.2 ± 3.2 d (adults)