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MYP_092964
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Basic Information
Bombinin-BO1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C111H188N30O31
Standard
Sequence
GIGSAILSAGKSIIKGLAKGLAEHF
Physicochemical Analysis
2438.86 Da
9.70
1.85
1.59
0.0739
0.66
0.67
0.34
-6.84
125.20
0.0400
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
966.45
-8.97
34.0
34.0
85.0
172.0
2.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0160394 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0197926 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HepG2
3.75 μM
IC50
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0273101 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
52.5 μM
MIC
PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0281319 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
SK-HEP-1
0.76 μM
IC50
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0285084 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
26.3 μM
MIC
PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
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