‹ ›
MYP_092906
← PREVIOUS NEXT → BACK
Basic Information
r8-BidBH3Alt
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C141H254N66O39S
Standard
Sequence
RRRRRRRRGEDIIRNIARHAAQVGASMDR
Physicochemical Analysis
3530.01 Da
12.00
7.85
7.60
0.2708
-1.55
0.90
-0.80
164.02
64.14
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1806.01
-23.33
70.0
49.0
126.0
247.0
1.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0193760 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
rrrrrrrr=D-isomer homopolymer of eight arginine residues
Bio-Activity Profile
Antimicrobial Anticancer
IMR-5 (1% apoptosis at 20 μM)
PaperPubMed PMID: 16568093 PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0204060 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
SK-N-AS
50 μM
Concentration response
PaperBH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0248016 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
NGP
50 μM
Concentration response
PaperBH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0255011 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
NGP
10 μM
Concentration response
PaperBH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0274306 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
FIRST PREV 1 2 3 4 5 6 NEXT LAST
Showing 5 records on this page · Page 3 of 6