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MYP_092903
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Basic Information
Pleurocidin [G13A][G17A]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C131H196N36O29
Standard
Sequence
GWGSFFKKAAHVAKHVAKAALTHYL
Physicochemical Analysis
2739.18 Da
10.18
4.02
3.65
0.1607
0.11
0.60
0.20
18.56
78.40
0.1600
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1028.32
-6.24
37.0
36.0
87.0
196.0
8.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0277023 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli IFO 12734
2 μg/mL
MIC
PMID11168895;14965277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0281165 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/14965277/ PMID14965277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14965277/
RECORD: Rec_0321418 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Rabbit erythrocytes
100 μM
Hemolysis
PaperYoshida K, Mukai Y, Niidome T, et al. Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity. J Pept Res. 2001 Feb;57(2):119-126. doi:10.1034/j.1399-3011.2001.00802.x. PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0330517 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
100 μM
HC50
PMID11168895;14965277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0353994 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa KCTC 1637
1 μM
MIC
PMID11168895;14965277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
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