Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitory peptide

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC48H75N11O11

DescriptionStandard

        VTPVGVPKW
    

Molecular Weight982.18 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)0.73

Net Charge (pH 7.4) 0.52

Charge Density (pH 7.0) 0.0814

GRAVY Index0.39

Hydrophobic Moment 0.14

Boman Index0.36

Instability Index32.82

Aliphatic Index 96.67

Aromaticity 0.1111

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 340.58

LogP -0.88

H-bond Donors 11.0

H-bond Acceptors 12.0

Rotatable Bonds 25.0

Heavy Atoms 70.0

Ring Count 4.0

Amide Bonds 8.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0284721 VERIFIED: YES

Provenance & Taxonomy

OrganismNigella sativa [Plant]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity1.8±0.09 μM

MethodIC50