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MYP_092860
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Basic Information
Hymenochirin-5Pg
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
23 amino acids
C117H203N27O30S
Standard
Sequence
ITIPPIVKDTLKKFIKGAISSVM
Physicochemical Analysis
2500.09 Da
10.00
2.76
2.55
0.1199
0.67
0.71
0.26
-1.18
131.30
0.0435
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
908.24
-4.95
31.0
34.0
84.0
175.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0117101 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0139470 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
20 μM
MIC
RECORD: Rec_0271834 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25726
40 μM
MIC
PMID24212286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0286482 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
20 μM
MIC
PMID24212286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24212286/
RECORD: Rec_0322943 VERIFIED: YES
Provenance & Taxonomy
Pseudhymenochirus merlini [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
20 μM
MIC
PaperCharacterization of the host-defense peptides from skin secretions of Merlin's clawed frog Pseudhymenochirus merlini: Insights into phylogenetic relationships among the Pipidae
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