Peptide Database

Peptide NameLantibiotic lichenicidin VK21 A1 (LchA1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC353H569N95O113S8

DescriptionStandard

        MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGGTITLSTCAILSKPLGNNGYLCTVTKECMPSCN
    

Molecular Weight8208.38 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.35

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.42

Hydrophobic Moment 0.55

Boman Index0.01

Instability Index78.59

Aliphatic Index 71.22

Aromaticity 0.0541

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3350.27

LogP -37.31

H-bond Donors 118.0

H-bond Acceptors 123.0

Rotatable Bonds 275.0

Heavy Atoms 569.0

Ring Count 11.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401604 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus licheniformis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

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