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MYP_092854
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Basic Information
Lantibiotic lichenicidin VK21 A1 (LchA1)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
74 amino acids
C353H569N95O113S8
Standard
Sequence
MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGGTITLSTCAILSKPLGNNGYLCTVTKECMPSCN
Physicochemical Analysis
8208.38 Da
6.70
-0.35
-0.75
-0.0048
-0.42
0.55
0.01
78.59
71.22
0.0541
9970.00
10220.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3350.27
-37.31
118.0
123.0
275.0
569.0
11.0
80.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0103381 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli (Gram-negative)
PMID20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20578714/
RECORD: Rec_0162434 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Lantibiotic
279010
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-MRSA Non-hemolytic
No Target Organism Found
PMID15461803;15383718;19561184;19707558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15461803/
RECORD: Rec_0206313 VERIFIED: NO
Provenance & Taxonomy
Bacillus [Bacterium]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ7076
RECORD: Rec_0227906 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic
B. pumilus (Gram-positive)
PMID20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20578714/
RECORD: Rec_0279534 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic
B. amyloliquefaciens (Gram-positive)
PMID20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20578714/
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