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MYP_092854
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Basic Information
Lantibiotic lichenicidin VK21 A1 (LchA1)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
74 amino acids
C353H569N95O113S8
Standard
Sequence
MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGGTITLSTCAILSKPLGNNGYLCTVTKECMPSCN
Physicochemical Analysis
8208.38 Da
6.70
-0.35
-0.75
-0.0048
-0.42
0.55
0.01
78.59
71.22
0.0541
9970.00
10220.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3350.27
-37.31
118.0
123.0
275.0
569.0
11.0
80.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015594 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Rhodococcus sp. (Gram-positive)
PMID20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20578714/
RECORD: Rec_0025994 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic
M. smegmatis (Gram-positive)
PMID20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20578714/
RECORD: Rec_0044415 VERIFIED: NO
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2023/0416797 A1 Evidence URLhttps://patents.google.com/patent/US20230416797A1/en PatentUS 2023/0416797 A1
RECORD: Rec_0044984 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Pseudomonas aeruginosa (Gram-negative)
PMID20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20578714/
RECORD: Rec_0099121 VERIFIED: NO
Provenance & Taxonomy
Bacillus licheniformis CG-B52 [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ6922
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