Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC306H478N82O91S8

DescriptionStandard

        MGILVLVFIFISLTQHGKNAHGPDSCNHGGGLCRMGSCVSGEYVAQYCFEPIILCCKNPTPATTES
    

Molecular Weight7018.08 Da

Isoelectric Point (pI)6.22

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.76

Charge Density (pH 7.0) -0.0196

GRAVY Index0.28

Hydrophobic Moment 0.44

Boman Index0.22

Instability Index29.17

Aliphatic Index 81.21

Aromaticity 0.0758

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2706.82

LogP -29.03

H-bond Donors 97.0

H-bond Acceptors 101.0

Rotatable Bonds 223.0

Heavy Atoms 487.0

Ring Count 12.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0169915 VERIFIED: NO

Provenance & Taxonomy

OrganismTaeniopygia guttata [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence