Peptide Database

Peptide NameBrevinin-1OS (1-3, 3-11)[P4K, G5W, I6A, V9W, N12K]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC75H111N17O13

DescriptionStandard

        FLPKWALKWAAK
    

Molecular Weight1458.79 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.2298

GRAVY Index0.06

Hydrophobic Moment 0.48

Boman Index0.20

Instability Index-6.91

Aliphatic Index 90.00

Aromaticity 0.2500

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 484.27

LogP 1.47

H-bond Donors 17.0

H-bond Acceptors 16.0

Rotatable Bonds 44.0

Heavy Atoms 105.0

Ring Count 6.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394156 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans NCPF 1467

Activity64 μM

MethodMIC

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