Peptide Database

Peptide NameBelatacept

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Immunomodulation ▸ Immunosuppressive

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1240H1948N326O389S13

DescriptionStandard

        MHVAQPAVVLASSRGIASFVCEYASPGKYTEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYEGIGNGTQIYVIDPEPCPDSDQEPKSSDKTHTSPPSPAPELLGGSSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPRE
    

Molecular Weight28063.53 Da

Isoelectric Point (pI)5.33

Net Charge (pH 7.0)-7.09

Net Charge (pH 7.4) -7.75

Charge Density (pH 7.0) -0.0278

GRAVY Index-0.36

Hydrophobic Moment 0.55

Boman Index0.01

Instability Index43.47

Aliphatic Index 75.96

Aromaticity 0.0745

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29255.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422533 VERIFIED: YES

Provenance & Taxonomy

OrganismCricetulus griseus [Animal]

FamilyFusion protein

Tax ID10029

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Immunosuppressive T-cell costimulation blocker

Half-LifeMean terminal elimination half-life- 9.8 d.