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MYP_092759
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Basic Information
Oncocin [R19H]
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
19 amino acids
C109H171N35O25
Standard
Sequence
VDKPPYLPRPRPPRRIYNH
Physicochemical Analysis
2371.74 Da
10.93
3.82
3.55
0.2010
-1.67
0.50
-0.47
62.05
56.32
0.1053
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
957.53
-6.70
32.0
30.0
66.0
169.0
9.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0249471 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
128 μg/mL
MIC
PMID21185160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185160/
RECORD: Rec_0299609 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli BL21AI
16 μg/mL
MIC
PMID21185160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185160/
RECORD: Rec_0359584 VERIFIED: YES
Provenance & Taxonomy
Oncopeltus [Animal]
Oncocin
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Har=Homoarginine
Bio-Activity Profile
Antimicrobial
8 μg/mL
MIC
25% mouse serum, in vivo; 5640 s
PaperBactericidal oncocin derivatives with superior serum stabilities PMID21185160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185160/
RECORD: Rec_0385316 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli BL21AI
16 μg/mL
MIC
Mouse serum: The half-life is 90 ±1 min in 25% aqueous mouse serum
PaperKnappe D, Kabankov N, Hoffmann R Bactericidal oncocin derivatives with superior serum stabilities Int J Antimicrob Agents. 2011 Feb;37(2):166-70. PMID:21185160 https://pubmed.ncbi.nlm.nih.gov/21185160/ PMID21185160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185160/
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