Peptide Database

Peptide NameCycloviolacin O7

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC133H210N32O36S6

DescriptionStandard

        TFPCGESCVWIPCISKVIGCACKSKVCY
    

Molecular Weight3025.67 Da

Isoelectric Point (pI)8.28

Net Charge (pH 7.0)1.34

Net Charge (pH 7.4) 1.05

Charge Density (pH 7.0) 0.0478

GRAVY Index0.76

Hydrophobic Moment 0.55

Boman Index0.26

Instability Index37.28

Aliphatic Index 76.43

Aromaticity 0.1071

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1063.74

LogP -9.01

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 93.0

Heavy Atoms 207.0

Ring Count 6.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0082389 VERIFIED: YES

Provenance & Taxonomy

OrganismViola biflora [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)