Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC472H771N123O133S9

DescriptionStandard

        MKLFLVLIILQFEVPTDTARPRKCFSTITGYCRKKCGIGEIYEMACVNGKLCCVNEDKNKKHKKAPESPHSLPQPDGMIDYVILPTTTLITVQL
    

Molecular Weight10585.50 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0385

GRAVY Index-0.07

Hydrophobic Moment 0.49

Boman Index0.04

Instability Index40.36

Aliphatic Index 92.23

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4088.81

LogP -33.94

H-bond Donors 144.0

H-bond Acceptors 148.0

Rotatable Bonds 352.0

Heavy Atoms 737.0

Ring Count 15.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224708 VERIFIED: NO

Provenance & Taxonomy

OrganismCallorhinus ursinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence