Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length528 amino acids

Chemical FormulaC2609H4182N696O729S16

DescriptionStandard

        MARSRNTLKPSTAARRQAFKRLGYTTGIEGRGTVCILLGTAEAARCLLTAVRMVVRSLALAALMLAACMVLARATNPGFVARITEKGLDYARKEGIAALEKKLAKLKLPDFSGSFKVKPFGNVHYEFYSLDLHSFQLPSSQIVPVPNVGLRVSVSKAFAQLTGKWKVKKRFIKDHGSFDLKVEGISISIGLKLGSDASGRPTVTTSECSTQISNVRVHISGRFGWLYNLFHKKIESSFRKTMESKVCGEVTSSVSTQLQPYLQTLPVTTKIDKVAGIDYSLVAPPVATAQSLDVNLKGEFFSLAHRSPAPFPPTALAFPSEHDRMVYLGASSYFFNTAGFVYQTAGVLVFNITDDMVPKGVEFHLNTSTFSAFIPQLEKLYPDRLMKLQVMTSSAPSLTITPGGLSLMPVVDIQAYAILSNSSLAPLFLLSLTSNISATVAVNSSRIGGTLALGRLKLSLKHSDVGPFSVQLLQSLMNFYGSKILLPRLNERLKAGFPLPLPDRIKLSSILLQPHQNFLLLAADVHYG
    

Molecular Weight57476.38 Da

Isoelectric Point (pI)9.88

Net Charge (pH 7.0)26.43

Net Charge (pH 7.4) 25.47

Charge Density (pH 7.0) 0.0500

GRAVY Index0.15

Hydrophobic Moment 0.71

Boman Index0.12

Instability Index40.58

Aliphatic Index 99.92

Aromaticity 0.0852

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 32110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111739 VERIFIED: NO

Provenance & Taxonomy

OrganismAlligator sinensis [Animal]

FamilyBPI/LBP

Tax ID38654

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria