Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC246H418N74O79S8

DescriptionStandard

        MSTKDFNLHLVSVSKKNSGASPRITSVSLCTPGCKTGAVMGCNMKTATCNCSIHVSK
    

Molecular Weight5932.92 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 5.22

Charge Density (pH 7.0) 0.0986

GRAVY Index-0.00

Hydrophobic Moment 0.32

Boman Index0.03

Instability Index25.51

Aliphatic Index 64.91

Aromaticity 0.0175

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2463.83

LogP -36.03

H-bond Donors 92.0

H-bond Acceptors 95.0

Rotatable Bonds 199.0

Heavy Atoms 407.0

Ring Count 5.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295292 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus faecium [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria