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MYP_092606
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Basic Information
Gaegurin-5 (1-13)[F6W,K7H,V8A,A9L,V12L], LL-1a
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C73H113N17O15
Standard
Sequence
FLGALWHALSKLL
Physicochemical Analysis
1468.78 Da
8.76
0.85
0.59
0.0651
1.25
0.44
0.53
32.60
165.38
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
503.24
0.17
18.0
17.0
46.0
105.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0114959 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Listeria monocytogenes
8 μM
MIC
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0134235 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MCF-10A
65 μM
IC50
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0163756 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
22 μM
IC50
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0169438 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: 15% Hemolysis=30 μM
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0182498 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis ATCC 9709
4 μM
MIC
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
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