‹ ›
MYP_092606
← PREVIOUS NEXT → BACK
Basic Information
Gaegurin-5 (1-13)[F6W,K7H,V8A,A9L,V12L], LL-1a
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C73H113N17O15
Standard
Sequence
FLGALWHALSKLL
Physicochemical Analysis
1468.78 Da
8.76
0.85
0.59
0.0651
1.25
0.44
0.53
32.60
165.38
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
503.24
0.17
18.0
17.0
46.0
105.0
4.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0005285 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli O157
64 μM
MIC
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0022284 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PANC-1
39 μM
IC50
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0023314 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human pancreatic carcinoma Panc-1
39 μM
IC50
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0063962 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus ATCC 10420
2 μM
MIC
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
RECORD: Rec_0092860 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Normal breast cells MCF-10a
65 μM
IC50
PMID22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22526264/
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3