Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC454H716N132O142S9

DescriptionStandard

        MNPLGTACFAVLCLFAIVSTGNGFPQESADQVQYFANTLFDELPEQSYQAAAENLRLKRATCDLLSGLGVNDSACAAHCIARGNRGGYCNSKKVCVCRN
    

Molecular Weight10583.93 Da

Isoelectric Point (pI)6.51

Net Charge (pH 7.0)-0.48

Net Charge (pH 7.4) -0.88

Charge Density (pH 7.0) -0.0049

GRAVY Index0.01

Hydrophobic Moment 0.61

Boman Index0.06

Instability Index36.21

Aliphatic Index 77.98

Aromaticity 0.0808

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4426.55

LogP -53.69

H-bond Donors 158.0

H-bond Acceptors 152.0

Rotatable Bonds 346.0

Heavy Atoms 737.0

Ring Count 12.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057440 VERIFIED: NO

Provenance & Taxonomy

OrganismCulex quinquefasciatus [Animal]

FamilyDefensin

Tax ID7176

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal