‹ ›
MYP_092511
← PREVIOUS NEXT → BACK
Basic Information
Actinomycesin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
36 amino acids
C171H253N55O50S6
Standard
Sequence
GFGCPWNAYECDRHCVSKGYTGGNCRGKIRQTCHCY
Physicochemical Analysis
4071.57 Da
8.65
2.87
2.47
0.0798
-0.78
0.35
-0.14
32.49
21.67
0.1389
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1709.17
-21.14
67.0
61.0
128.0
282.0
9.0
38.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0231311 VERIFIED: YES
Provenance & Taxonomy
Actinomyces sp [Bacterium]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Immunomodulatory
bacterial cell wall synthesis, likely by binding to the precursor molecule membrane-anchored Lipid II
PaperAdaptively evolved human oral actinomyces-sourced defensins show therapeutic potential.
RECORD: Rec_0234092 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Defensin
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID34927385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34927385/
RECORD: Rec_0249877 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Defensin
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID34927385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34927385/
RECORD: Rec_0255920 VERIFIED: YES
Provenance & Taxonomy
Actinomyces sp. oral taxon 171 str. F0337 [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-25; 11-33; 15-35
Bio-Activity Profile
Antimicrobial Host defense
PaperPDB 2RU0 structural record; NMR; chain A; residues 1-36
RECORD: Rec_0263199 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Defensin
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PMID34927385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34927385/