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MYP_092490
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Basic Information
Actinomycin Z5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
5 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XVXXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021797 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID10757717 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10757717/
RECORD: Rec_0079533 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
dolastatin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Non-proteinogenic/modified monomers: Dov; Dil; Dap; Doe
Bio-Activity Profile
Anticancer
RECORD: Rec_0085070 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID10757717 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10757717/
RECORD: Rec_0260049 VERIFIED: YES
Provenance & Taxonomy
Bacteria [Bacterium]
Structure & Mods
linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID10757717 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10757717/
RECORD: Rec_0405031 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cyclic peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum Indochina W2
Fluorimetry (PicoGreen)
PMID17441769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17441769/