Peptide Database

Peptide NameS17

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC137H226N52O32S2

DescriptionStandard

        EMFTILEEYFMYRRRRRRRRRR
    

Molecular Weight3177.72 Da

Isoelectric Point (pI)11.83

Net Charge (pH 7.0)6.84

Net Charge (pH 7.4) 6.66

Charge Density (pH 7.0) 0.3109

GRAVY Index-1.87

Hydrophobic Moment 0.35

Boman Index-0.95

Instability Index270.52

Aliphatic Index 35.45

Aromaticity 0.1818

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1466.01

LogP -11.83

H-bond Donors 59.0

H-bond Acceptors 41.0

Rotatable Bonds 111.0

Heavy Atoms 223.0

Ring Count 4.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0171544 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays