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MYP_092477
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Basic Information
RV-23
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
23 amino acids
C126H219N33O25S
Standard
Sequence
RIGVLLARLPKLFSLFKLMGKKV
Physicochemical Analysis
2628.36 Da
12.00
5.76
5.55
0.2503
0.75
0.65
0.15
-3.36
148.26
0.0870
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
942.84
-2.24
34.0
32.0
92.0
185.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0305914 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
40 μM
MIC
PMID16307827 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16307827/
RECORD: Rec_0306916 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0308208 VERIFIED: YES
Provenance & Taxonomy
Rana aurora [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PaperPubMed PMID: 16307827 | Design of an α-helical antimicrobial peptide with improved cell-selective and potent anti-biofilm activity. Sci Rep. 2016 Jun 8;6:27394. doi: 10.1038/srep27394. PMID: 27271216. PMID16307827;27271216 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16307827/
RECORD: Rec_0333033 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
80 μM
MIC
PMID16307827 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16307827/
RECORD: Rec_0400615 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
RV
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
35.0 μM
HC50
PaperE. Urban et al. / International Journal of Antimicrobial agents 29 (2007) 317-321. Activities of four frog skin-derived antimicrobial peptides (temporin-1DRa, temporin-1Va and the melittin-related peptides AR-23 and RV-23) against anaerobic bacteria
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