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MYP_092477
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Basic Information
RV-23
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
23 amino acids
C126H219N33O25S
Standard
Sequence
RIGVLLARLPKLFSLFKLMGKKV
Physicochemical Analysis
2628.36 Da
12.00
5.76
5.55
0.2503
0.75
0.65
0.15
-3.36
148.26
0.0870
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
942.84
-2.24
34.0
32.0
92.0
185.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033489 VERIFIED: NO
Provenance & Taxonomy
Rana draytonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic
RECORD: Rec_0058971 VERIFIED: YES
Provenance & Taxonomy
Rana aurora [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
6.25 μM
MIC
PaperPubMed PMID: 16307827 | Design of an α-helical antimicrobial peptide with improved cell-selective and potent anti-biofilm activity. Sci Rep. 2016 Jun 8;6:27394. doi: 10.1038/srep27394. PMID: 27271216. PMID16307827;27271216 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16307827/
RECORD: Rec_0097327 VERIFIED: YES
Provenance & Taxonomy
Rana aurora [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PaperPubMed PMID: 16307827 | Design of an α-helical antimicrobial peptide with improved cell-selective and potent anti-biofilm activity. Sci Rep. 2016 Jun 8;6:27394. doi: 10.1038/srep27394. PMID: 27271216. PMID16307827;27271216 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16307827/
RECORD: Rec_0105978 VERIFIED: YES
Provenance & Taxonomy
Rana aurora [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcuss aureus
12.5 μM
MIC
PaperPubMed PMID: 16307827 | Design of an α-helical antimicrobial peptide with improved cell-selective and potent anti-biofilm activity. Sci Rep. 2016 Jun 8;6:27394. doi: 10.1038/srep27394. PMID: 27271216. PMID16307827;27271216 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16307827/
RECORD: Rec_0140157 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
2.5 μM
MIC
PMID16307827 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16307827/
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