Peptide Database

Peptide NameC-terminal Filaggrin-2 derived peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC148H207N47O45

DescriptionStandard

        ERQLHGSGIGWRHGSYGSADYEYRHSGFGP
    

Molecular Weight3364.51 Da

Isoelectric Point (pI)7.12

Net Charge (pH 7.0)0.10

Net Charge (pH 7.4) -0.23

Charge Density (pH 7.0) 0.0033

GRAVY Index-1.22

Hydrophobic Moment 0.33

Boman Index-0.11

Instability Index9.49

Aliphatic Index 29.33

Aromaticity 0.1667

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1482.56

LogP -17.57

H-bond Donors 54.0

H-bond Acceptors 48.0

Rotatable Bonds 105.0

Heavy Atoms 240.0

Ring Count 10.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0233260 VERIFIED: YES

Provenance & Taxonomy

OrganismGaleopterus variegatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)