‹ ›
MYP_092415
← PREVIOUS NEXT → BACK
Basic Information
RN7-IN9(designed based on indolicidin and ranalexin)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C109H152N28O17
Standard
Sequence
FLGGLIKKWPWWPWRR
Physicochemical Analysis
2126.55 Da
12.00
3.76
3.55
0.2349
-0.59
0.50
0.07
43.98
73.12
0.3125
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
721.24
2.01
27.0
21.0
61.0
154.0
11.0
15.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0014625 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
7.81 μg/mL
MIC
PaperAntimicrobial Activity of Novel Synthetic Peptides Derived from Indolicidin and Ranalexin against Streptococcus pneumoniae. PLoS One. 2015 Jun 5;10(6):e0128532. doi: 10.1371/journal.pone.0128532. PMID: 26046345. PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
RECORD: Rec_0034886 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumanii ATCC 15308
31.25 μg/mL
MIC
PaperAntimicrobial Activity of Novel Synthetic Peptides Derived from Indolicidin and Ranalexin against Streptococcus pneumoniae. PLoS One. 2015 Jun 5;10(6):e0128532. doi: 10.1371/journal.pone.0128532. PMID: 26046345. PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
RECORD: Rec_0069100 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 15442
31.25 μg/mL
MIC
PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
RECORD: Rec_0073703 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 15442
31.25 μg/mL
MIC
PaperAntimicrobial Activity of Novel Synthetic Peptides Derived from Indolicidin and Ranalexin against Streptococcus pneumoniae. PLoS One. 2015 Jun 5;10(6):e0128532. doi: 10.1371/journal.pone.0128532. PMID: 26046345. PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
RECORD: Rec_0089111 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human RBCs
PaperAntimicrobial Activity of Novel Synthetic Peptides Derived from Indolicidin and Ranalexin against Streptococcus pneumoniae. PLoS One. 2015 Jun 5;10(6):e0128532. doi: 10.1371/journal.pone.0128532. PMID: 26046345. PMID26046345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26046345/
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5