Peptide Database

Peptide NameGallinacin-4 (Gal-4; Beta-defensin 4; Birds, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC193H289N59O48S7

DescriptionStandard

        RYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRWL
    

Molecular Weight4428.18 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.87

Net Charge (pH 7.4) 5.47

Charge Density (pH 7.0) 0.1544

GRAVY Index-0.56

Hydrophobic Moment 0.47

Boman Index-0.10

Instability Index37.54

Aliphatic Index 33.42

Aromaticity 0.1579

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1714.23

LogP -16.60

H-bond Donors 68.0

H-bond Acceptors 63.0

Rotatable Bonds 135.0

Heavy Atoms 307.0

Ring Count 12.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398579 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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