‹ ›
MYP_092395
← PREVIOUS NEXT → BACK
Basic Information
FIV Egp (734-768)
Anticancer
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
35 amino acids
C191H297N51O60S
Standard
Sequence
EWYNQTKDLQQKFYEIIMDIEQNNVQGKKGIQQLQ
Physicochemical Analysis
4299.77 Da
4.94
-1.16
-1.34
-0.0332
-1.20
0.59
-0.18
56.34
75.14
0.1143
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1893.77
-17.12
60.0
60.0
153.0
303.0
5.0
45.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0267444 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
N-terminal Acetylation; C-terminal Amidation
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0300229 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
N-terminal Acetylation; C-terminal Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic Anticancer
HeLa cells
23 μM
Cytotoxicity
PaperPubMed PMID: 12186891 PMID12186891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12186891/
RECORD: Rec_0382670 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
N-terminal Acetylation; C-terminal Amidation
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1; CEM4/IIIB cells; MOLT-4 cells
2.304 μM
Cell-cell fusion inhibition
PaperPubMed PMID: 12186891 PMID12186891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12186891/
RECORD: Rec_0405787 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
N-terminal Acetylation; C-terminal Amidation
Bio-Activity Profile
Antiviral Anti-FIV Fusion inhibition
Feline immunodeficiency virus (FIV); FIV/CrFK cells; HeLa cells
0.054 μM
EC90
Mammalian: 1 h; Yeast: 30 min; E. coli: >10 h
PaperC-Terminal gp40 peptide analogs inhibit feline immunodeficiency virus: cell fusion and virus spread. | Medinas RJ, Lambert DM, Tompkins WA. | J Virol. 2002 Sep;76(18):9079-86. | DOI:10.1128/jvi.76.18.9079-9086.2002 | PMID:12186891 PMID12186891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12186891/
RECORD: Rec_0426136 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
N-terminal Acetylation; C-terminal Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 12186891 PMID12186891 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12186891/
FIRST PREV 1 2 3
Showing 5 records · Page 3 of 3