Peptide Database

Peptide Name[R9S-R14S-R17S]cTI

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC92H136N26O24S4

DescriptionStandard

        KWCFRVCYSGICYSRCSG
    

Molecular Weight2118.48 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)2.72

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.1510

GRAVY Index0.11

Hydrophobic Moment 0.48

Boman Index0.00

Instability Index15.43

Aliphatic Index 37.78

Aromaticity 0.2222

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 824.78

LogP -8.18

H-bond Donors 36.0

H-bond Acceptors 31.0

Rotatable Bonds 65.0

Heavy Atoms 146.0

Ring Count 5.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0129164 VERIFIED: YES

Provenance & Taxonomy

Organismhost defense peptide from the horseshoe crab Tachypleus tridentatus [other]

Structure & Mods

Configcyclic/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0160216 VERIFIED: YES

Provenance & Taxonomy

Organismhost defense peptide from the horseshoe crab Tachypleus tridentatus [other]

Structure & Mods

Configcyclic/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

Activity4.8±0.3 μM

MethodCC50

RECORD: Rec_0171967 VERIFIED: YES

Provenance & Taxonomy

Organismhost defense peptide from the horseshoe crab Tachypleus tridentatus [other]

Structure & Mods

Configcyclic/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetWM164

Activity11.1±0.9 μM

MethodCC50

RECORD: Rec_0371773 VERIFIED: YES

Provenance & Taxonomy

Organismhost defense peptide from the horseshoe crab Tachypleus tridentatus [other]

Structure & Mods

Configcyclic/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0399557 VERIFIED: YES

Provenance & Taxonomy

Organismhost defense peptide from the horseshoe crab Tachypleus tridentatus [other]

Structure & Mods

Configcyclic/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetHT-144

Activity11.8±0.9 μM

MethodCC50