Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length143 amino acids

Chemical FormulaC671H1076N188O210S16

DescriptionStandard

        MREPPEGALSSNGAPRIIGTRKPLHHDKVEKSEELTRVTCTRVKAQNQLEQFSPPEMKTFSVAVVAAVLLALICLQESSALPLSEVEDVEVPVMDDNGAAVYEEMPVDSWKMPYTNRHKRSPAGCKFCCNCCGMSGCGVCCDF
    

Molecular Weight15649.90 Da

Isoelectric Point (pI)5.38

Net Charge (pH 7.0)-4.30

Net Charge (pH 7.4) -4.86

Charge Density (pH 7.0) -0.0301

GRAVY Index-0.21

Hydrophobic Moment 0.44

Boman Index-0.01

Instability Index61.70

Aliphatic Index 71.54

Aromaticity 0.0490

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 9105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6323.00

LogP -68.23

H-bond Donors 223.0

H-bond Acceptors 225.0

Rotatable Bonds 512.0

Heavy Atoms 1085.0

Ring Count 22.0

Amide Bonds 151.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0360333 VERIFIED: NO

Provenance & Taxonomy

OrganismTakifugu flavidus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal