Peptide Database

Peptide NameCholecystokinin-58 desnonopeptide

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC233H391N77O69S

DescriptionStandard

        AVQKVDGEPRAHLGALLARYIQQARKAPSGRMSVIKNLQNLDPSHRISD
    

Molecular Weight5407.14 Da

Isoelectric Point (pI)10.41

Net Charge (pH 7.0)3.98

Net Charge (pH 7.4) 3.67

Charge Density (pH 7.0) 0.0811

GRAVY Index-0.58

Hydrophobic Moment 0.67

Boman Index-0.16

Instability Index30.46

Aliphatic Index 93.67

Aromaticity 0.0204

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2387.56

LogP -27.06

H-bond Donors 82.0

H-bond Acceptors 76.0

Rotatable Bonds 183.0

Heavy Atoms 380.0

Ring Count 6.0

Amide Bonds 54.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0015767 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyCholecystokinin-58 desnonopeptide

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0097704 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyGastrin/cholecystokinin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide

RECORD: Rec_0135993 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyCholecystokinin-58 desnonopeptide

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

CCK receptor agonist Gastrointestinal secretion Receptor modulation Hormone Endocrine Neuropeptide Neuromodulator Myotropic

TargetCCK-A receptor; CCK-B receptor

MethodReceptor-mediated amylase and gastric secretion assay

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour